摘要
慢性排斥仍然是导致肾移植失败的主要原因。慢性排斥的发病机制尚不十分清楚 ,主要包括免疫和非免疫因素。作者就移植肾慢性排斥的临床和病理诊断、免疫和非免疫性因素方面的最新研究进展作一综述 ,旨在探讨慢性排斥发生的原因 。
Chronic rejection accounts for most renal allograft losses after the first year posttransplantation.Growing evidence indicates that chronic rejection is the aggregate sum of irreversible immunologic and nonimmunologic injuries to the renal graft over time.Clinical management of renal transplant recipients should incorporate both immunologic and nonimmunologic based intervention strategies aimed at minimizing risk factors to thwart the progression of chronic rejection and improve long term allograft and patient survival.
出处
《医学研究生学报》
CAS
2003年第2期142-144,共3页
Journal of Medical Postgraduates
关键词
慢性排斥
肾移植
肾活检
免疫抑制剂
血肌酐
Chronic rejection
Renal transplant
Renal biopsy
Immunosuppression
Serum creatinine
