皂化—冷析法精制天然维生素E工艺的研究

Study on the Purification of Natur al Vitamin E by Saponification and Crystallization

以提高天然VE 产品比旋光度为目的 ,用皂化与结晶相结合的方法对天然VE 浓缩物进行提纯。实验中选用了丙酮 ,95 %丙酮 ,乙醇 ,95 %乙醇四种溶剂进行了结晶实验 ,并对比了皂化与不皂化对产品比旋光度的影响 ,发现经过皂化后的产品比未经过皂化的产品比旋光度提高 + 5°左右。此外通过二次皂化后 ,产品的比旋光度基本可以达到FCC标准 (比旋光度 [α]2 5D ≥ + 2 0°)。

In this thesis, a process of purification vitam in E by saponification and crystallization from the secondary products of the deod orization is adopted. Four frequent used solvents(acetone,95% acetone, ethanol, 95% ethanol) were examined in this article. Through comparing the specific rotation of products that treat ed without saponification, we find that the products treated with saponifica tion have the higher specific rotation. In addition, under the multiple saponifi cation, the specific rotation of vitamin E can be improved to 20°.