某院Ⅰ～Ⅱ类切口围术期患者点评前后预防用抗菌药物的合理性分析

Rationlity Analysis of Prophylactic Antimicrobial Agents before and after Evaluation in Patients with TypeⅠand Ⅱ incision in A Hospital

目的:分析某院Ⅰ～Ⅱ类切口围术期患者点评前后预防用抗菌药物的合理性,为临床抗菌药物的合理使用提供参考。方法:选取2017年3月1日—7月31日期间医院Ⅰ～Ⅱ类切口手术患者2 101例资料作为对照组;另选取2018年3月1日—7月31日期间Ⅰ～Ⅱ类切口手术患者2 503例资料作为点评组,比较两组患者预防用抗菌药物的使用率、抗菌药物品种、用药时机、给药频次和疗程合理率的差异。结果:点评组患者I类切口抗菌药物预防使用率为26.98%低于对照组为69.99%(P<0.05),合理率为80.98%低于对照组为55.42%(P<0.05);点评组患者II类切口抗菌药物预防使用合理率为87.65%低于对照组为74.80%(P<0.05)。结论:通过药师点评及干预,有效遏制了医院Ⅰ～Ⅱ类切口围术期患者抗菌药物的不合理使用,极大提高了医院Ⅰ～Ⅱ类切口围术期患者抗菌药物使用的合理性,进一步降低了医院的药占比率,规范了医院临床抗菌药物的使用。

Objective: To analyze the Rationlity of prophylactic antimicrobial agents before and after evaluation in patients with typeⅠand Ⅱ incision in a hospital, and to provides a reference for the rational use of clinical antibacterial drugs. Methods: Data of 2 101 patients undergoing classⅠand Ⅱ incision surgery in hospital from March 1, 2017 to July 31, 2017 were selected as the control group. In addition, data of 2 503 patients undergoing classⅠand Ⅱ incision surgery from March 1 to July 31, 2018 were selected as the comment group. The difference of utilization rate, variety, timing, administration frequency and treatment course of prophylactic antibacterials were compared between the two groups. Results: I classes of antimicrobial drugs to prevent incision utilization rate in comment group patients was26.98% was lower than in control group of 69.99%(P<0.05). The reasonable rate of 80.98% was lower than that of55.42% in the control group(P<0.05). II class incision antibacterial drug prevention of the reasonable rate in comment group patients was 87.65% was lower than the control group of 74.80%(P<0.05). Conclusion: Through pharmacist’s comment and intervention, the irrational use of antibiotics in perioperative period of classⅠand Ⅱ incision was effectively curbed;the rationality of perioperative antibiotics application in classⅠand Ⅱ incision was greatly improved, the proportion of antibiotics was further reduced, and the clinical use of antibiotics in our hospital was standardized.