药学和行政干预前后对Ⅰ类切口手术患者预防性使用抗菌药物的合理性及其效果比较

Comparison on Rationality and Effectiveness of Prophylactic Antibiotics in Patients of Type Ⅰ Incision Operation before and after Interventions

目的:比较药学和行政干预前后对I类切口手术患者预防使用抗菌药物的合理性及其效果,为进一步加强管理提供参考。方法:选取2015年10—12月和2017年10—12月间I类切口手术患者预防使用抗菌药物的资料,比较和分析了其抗菌药物的使用率、使用品种、用药时机及疗程的合理性和效果。结果:联合干预后医院I类切口手术患者抗菌药预防的使用率为26.26%低于干预前为33.77%(P<0.05),用药品种、时机及疗程等较干预前更为合理。结论:药学和行政干预I类切口手术患者预防使用抗菌药物更趋于合理,显著提高了其合理性。

Objective: To compare the rationality and effectiveness of prophylactic antibiotics in patients of type ℃incision operation before and after pharmaceutical and administrative interventions and to provide reference for further strengthening management. Methods: Data on the prophylactic use of antimicrobial agents in patients with type I incision surgery from October and December 2015 and October ato December 2017 were selected to compare and analyze the utilization rate of antimicrobial agents, the variety of use, the timing of drug use and the rationality and effect of the course of treatment. Results: After combined intervention, the utilization rate of antimicrobial prophylaxis in patients undergoing hospital type I incision operation was 26.26%, lower than 33.77% before intervention(P<0.05). The variety,time and course of medication were more reasonable than those before intervention.