咽喉部梅毒8例临床特点分析

Clinical analysis of 8 patients with laryngeal andpharyngeal syphilis

目的: 分析以咽喉部疼痛、声嘶为首发症状的梅毒的临床特点,以避免对该病的误诊、误治。方法:对2000年8月-2002年6月作者在援助喀麦隆医疗队工作期间就诊于Guider医院首诊于耳鼻喉科的8例梅毒病进行了总结性分析。结果:8例患者均有口腔及咽喉部粘膜白色病损,经快速血浆反应素环状卡片试验(RPR)和梅毒螺旋体血凝试验(TPHA)进行梅毒血清血检查均呈阳性。经治疗1-2个疗程后均痊愈,复查RPR转阴,TPHA滴度下降,随访半年未复发。结论:咽喉部梅毒根据病史、临床特点和血清学检查均可确诊,不必取活组织病理检查。耳鼻喉科医生对本病应有足够的认识,避免误诊、误治。

Objective: To investigate the clinical characters of laryngeal and pharyngeal syphilis in order to avoid misdiagnosis. Method:Eight patients with laryngeal and pharyngeal syphilis were diagnosed and treated from August 2000 to June 2002 in Guider Hospital of Cameroon. There were 6 males and 2 females, ranging age from 21 to 53 years old. Result: The clinical signal and symptom showed hoarseness, pain and the white mucous membrane lesion in buccal cavity. The disease history suggested that they have harmful sexual behavior history. The test of rapid plasma reagin circle card test (RPR) and treponema pallidum hemagglutination assay (TPHA) were positive in all 8 patients. After 1-2 courses of therapy,they were cured fully,and their reexamination of RPR turned negative and the titer of TPHA test was dropped. After half year of follow-up, they did not recurrent of disease. Conclusion:On the base of the history,clinical characters and serology examination,the diagnosis of laryngeal and pharyngeal syphilis should be made easily and the biopsy is unnecessary.