摘要
目的:观察肾炎宁治疗小儿IgA肾病的临床疗效。方法:对25例IgA肾病患儿应用自拟方肾炎宁(由黄芪、党参、茯苓、白术、女贞子、旱莲草、生地黄、白茅根、川芎、白花蛇舌草、三七粉、仙鹤草组成)治疗。结果:完全缓解8例,显著缓解8例,好转6例,无效3例,总有效率为88%。无不良反应。治疗后尿红细胞排泄率与治疗前比较,差异有非常显著性意义(P<0.01);尿白蛋白定量、血清IgA、血β2-MG、尿β2-MG、尿Alb、尿α1-MG、尿IgG与治疗前比较,差异有显著性意义(P<0.05)。结论:肾炎宁治疗IgA肾病疗效确切,副作用小。
Objective:ToobservethecurativeeffectofShenyanNing(SN)forIgAnephropathininchildren.Methods:25casesweretreatedbySN(composedofRadixAstragali,RadixCodonopsis,Pori-a,RhizomaAtractylodisMacrocephalae,FructusLigustriLucidi,Her-baEcliptae,RadixRehmanniae.RhizomaImperata.RhizomaChuanxiong,herbaHedyotisDiffusae,PulvisNotogensengandHerbaAgrimoniae).Results:8caseswerecompletelyrelieved,8casesmarkedlyrelieved,6casesimprovedand3casesineffective,thetotaleffectiveratebeing88%.Noadversereactionwasobserved.Aftertreatment,urinaryRBCwasdecreased(P<0.01),andserumIgA,bloodandurinaryβ2-MG,urinaryAlb(qualitativelyandquantila-tively),α1-microglobulinandIgAalsoreduced(P<0.05).Con-clusion:SNpossessesdefinitecurativeeffectforIgAnephropathyinchildrenwithfewsideeffect.
出处
《新中医》
CAS
北大核心
2003年第4期16-17,共2页
New Chinese Medicine
基金
河北省科技厅科研计划项目(编号:00276205D)
关键词
肾小球肾炎
IGA
肾炎宁
儿童
glomerculonephritis
IgA
ShenyanNing
children