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荧光显微图像显示与分析系统

Fluorescence Microscopic Image Display and Analysis System
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摘要 荧光显微图像的质量受显微成像系统的自身限制,导致所记录的图像中存在不同程度的退化现象,针对此问题,许多增强观测图像质量或对比度的复原与重建算法被提出。在综合分析这些算法的基础上,设计并实现了基于二维图像复原和三维图像重建算法的荧光显微图像显示与分析系统,本系统的设计旨在将显微图像的二维复原与三维重建算法集成到一个显示界面中,使图像处理过程更加便利,处理结果更加直观。使用者可以选择不同的内嵌算法来达到不同的目的(去噪,去模糊,3D重建等),也可以通过设置不同的参数,观察其对图像复原的影响。 The quality of the fluorescence microscopic image is greatly degraded because of the physical limitation and human disturbance during the course of the optical imaging. Therefore,many image restoration and reconstruction algorithms were proposed to solve this problem. In this paper,an image display and analysis system for fluorescence microscopic sample was designed based on two-dimensional restoration and three-dimensional reconstruction algorithms. Our system aims to integrate those algorithms into one display interface,which is more convenient to process the images of fluorescence microscopic sample,and gives the more impressive results( denoising,deblurring,and 3D reconstruction etc.).User can obtain different restoration results by choosing different algorithms, and observe diverse restoration effects by setting different parameters.
出处 《科技通报》 2018年第1期159-163,共5页 Bulletin of Science and Technology
基金 国家自然基金面上项目(No.61671028) 北京市自然科学基金面上项目(No.4162018) 北京市委组织部“高创计划”青年技术人才培训资助项目(No.2014000026833ZK14) 北京市属高等学校高层次人才引进与培训计划项目(CIT&TCD201504010)
关键词 荧光 显微样本 系统 fluorescence microscopic sample system
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