基于二阶马尔可夫随机场的蛋白质功能预测
被引量：1
摘要
蛋白质功能预测是后基因组时代研究的热点问题,基于蛋白质交互网络的蛋白质功能预测方法受到越来越多研究者的关注。本文提出了蛋白质功能预测的二阶马尔可夫随机场模型,并利用伪似然估计方法对模型参数进行估计,在平均预测准确率的意义下,较一阶马尔可夫随机场模型取得了更好的预测效果。
出处
《科技信息》
2014年第12期79-79,共1页
Science & Technology Information
二级参考文献13
-
1Letovsky S, Kasif S. Predicting protein function from protein-protein interaction data:a probabilistic approach[ J]. Bioinformatics ,2003,19.197.
-
2Samanta MP, Liang S. Predicting protein functions from redundancies in large-scale protein interaction netwerks [ J ]. Proceedings of the National Academy of Sciences, 2003,100 : 12579.
-
3Vazquez A, Flammini A,Maritan A,et al. Global protein function prediction from protein-protein interaction networks [ J ]. Nat Biotechnol,2003,21 : 697.
-
4Salwinski L, Miller CS, Smith A J, et al. The Database of Interacting Proteins :2004 update [ J ]. Nucleic Acids Res, 2004,32 : D449.
-
5Bader GD, Betel D, Hogue CW. BIND: the biomolecular interaction network database [ J ]. Nucleic Acids Res, 2003,31:248.
-
6Chua HN, Sung WK, Wong L. Exploiting indirect neighhours and topological weight to predict protein function from protein-protein interactions [ J ]. Bioinformatics, 2006,22 : 1623.
-
7LaCount DJ, Vignali M, Chettier R, et al. A protein interaction network of the malaria parasite Plasmodium falciparum[ J ]. Nature,2005,438 : 103.
-
8Rual JF, Venkatesan K, Hao T, et al. Towards a proteomescale map of the human protein-protein interaction network[ J]. Nature,2005,437 : 1173.
-
9Nabieva E, Jim K, Agarwal A, et al. Wholeproteome prediction of protein function via graph-theoretic analysis of interaction maps [ J ]. Bioinformatics ,2005,21 : 302.
-
10Deng M, Zhang K, Mehta S, et al. Prediction of protein function using protein-protein interaction data[ J]. J Comput Biol,2003,10 (6) :947.
同被引文献20
-
1Hawkins T, Chitale M, Luban S, et al. PFP: Automated prediction of gene ontology functional annotations with confidence scores using protein sequence data. Proteins-structure Function & Bioinformatics, 2009, 74(3): 566-582.
-
2Altschul SF, Gish W, Miller W, et al. Basic local alignment search tool. Journal of Molecular Biology, 1990, 215(3): 403-410.
-
3Pearson WR. Rapid and sensitive sequence comparison with FASTP and FASTA. Methods in Enzymology, 1990, 183(1): 63-98.
-
4Altschul SF, Madden TL, Schaiffer AA, et al. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Research, 1997, 25(8): 3389-3402.
-
5Bujnicki J. Sequence permutations in the molecular evolution of dna methyl transferases. BMC Evolutionary Biology, 2: 3, 2002.
-
6Cunningham BA, Hemperly J J, Hopp TP, Edelman GM. Favin versus concanavalin A: Circularly permuted amino acid sequences. Proc. Natl. Aead. Sci. USA, 1979, 76(7): 3218-3222.
-
7Daly NL, Craik DJ. Acyclic permutants of naturally occurring cyclic proteins. The Journal of Biological Chemistry, 2000, 275(25): 3218-22.
-
8Craik DJ. Seamless proteins tie up their loose ends. Science, 2006, 311: 1563-1564.
-
9Craik DJ. Circling the enemy: Cyclic proteins in plant defence. Trends Plant Sci., 2009, 14(6): 328-335.
-
10Weiner J, Bomberg-Bauer E. Evolution of circular permutations in multidomain proteins. Mol. Biol. Evol, 2006, 23(4): 734-743.
-
1叶淑群.生命科学发展过程中物理学的贡献[J].现代物理知识,2007,19(3):68-70.
-
2黄志伟,黄勇平,杜家纬.蛋白质组学方法在昆虫学研究中的应用[J].昆虫知识,2007,44(1):37-41. 被引量：3
-
3高会江,杨润清.动态性状基因座的复合区间定位[J].科学通报,2006,51(13):1552-1557. 被引量：2
-
4谌建成.Poisson问题[J].中学教研（数学版）,1986,0(8):35-35.
-
5杨润清,高会江,孙华,Shizhong Xu.远交群体动态性状基因定位的似然分析 Ⅰ.理论方法[J].Acta Genetica Sinica,2004,31(10):1116-1122. 被引量：3
-
6杜焕强,沈才樑.融合多元生物数据预测蛋白相互作用关系[J].科技通报,2016,32(1):79-82.
-
7王晓芳,贾宗维.一种新的图划分算法在PPI网络模块化中的研究[J].山西农业大学学报（自然科学版）,2012,32(6):574-576.
-
8柴薇薇,普晓俊,乔岩,杨芳.蛋白质组学在植物逆境胁迫研究中的进展[J].生物学杂志,2013,30(6):70-75. 被引量：5
-
9沈庭芝.一种模拟自然纹理图象的神经网络模型[J].北京理工大学学报,1995,15(2):233-236.
-
10刘洪运,王卫东,谭小丹.蛋白质偶联分析似然算法的实现[J].科学技术与工程,2007,7(23):6021-6024.
