脉搏波传导速度与冠心病冠状动脉病变严重程度的相关性分析

Correlation Analysis of Pulse Wave Velocity and Severity of Coronary Heart Disease

目的探讨脉搏波传导速度与冠心病冠脉病变严重程度的相关性及其预测价值.方法昆明市延安医院心内科2011年8月至2012年8月收治的180例冠心病患者为冠心病组,根据冠状动脉造影结果中冠脉病变数量分为单支病变组(119例)和多支病变组(61例),根据严重程度分为轻度病变组(132例)和严重病变组(48例),同时选择同期的健康体检者180例作为健康组,对比健康组和冠心病组、单支病变组和多支病变组、轻度病变组和严重病变组的脉搏波传导速度差异.结果冠心病组患者脉搏波传导速度明显高于健康组,差异有统计学意义(P<0.05),多支病变组患者的脉搏波传导速度明显高于单支病变组,差异有统计学意义(P<0.05),轻度病变组患者的脉搏波传导速度明显低于严重病变组,差异有统计学意义(P<0.05).结论脉搏波传导速度与冠心病严重程度有明显的相关性,患者冠脉病变越严重,其脉搏波传导速度越大.

Objective To investigate the correlation of the pulse wave velocity and severity of coronary heart disease, and evaluate the predictive value. Methods 180 patients with coronary artery disease were enrolled as coronary disease group, which were devided into single-vessel group(n = 119) and multi-vessel group(n = 61) according to the lesion number,and into slight lesion group(n = 132) and severe lesion group(n = 48) according to the severity. 180 healthy people were chosen as healthy group in the corresponding period. The differences of pulse wave velocity between healthy group and coronary disease group, single-vessel group and multi-vessel group, slight lesion group and severe lesion group were analyzed. Res ults The pulse wave velocity of coronary disease group was apparently higher than that of healthy group, and the difference had statistical significance(P < 0.05). The pulse wave velocity of multi-vessel group was obviously higher than that of single-vessel group, and the difference had statistical significance(P < 0.05). The pulse wave velocity of slight lesion group was much lower than that of severe lesion group, and the difference between them was statistically significant(P < 0.05). Conclus ion The pulse wave velocity and the severity of coronary heart disease have a significant correlation, which patients with more severe disease have higher pulse wave velocity.