氮化纯钛颈椎植骨融合器的研制及生物力学测试

Design and biomechanical test of the titanium cervical spine fusion cage

目的:根据国人颈椎特点设计研制了一种经氮化处理的纯钛植骨融合器,并进行生物力学测试。方法:取12具新鲜成年男性颈椎标本,分别处理成包含单、双运动功能单位的试样,模拟前路植骨及植人融合器,进行前屈、后伸、侧弯、扭转四个方面的测试,比较本融合器植人后与完整颈椎及单纯椎间植骨的稳定性,经统计学分析后自编程序拟合出载荷—位移曲线和扭矩一扭转角曲线。同时进行疲劳强度和强度破坏试验。结果:融合器植人后颈椎在各方向运动中的稳定性均明显强于单纯椎间植骨,也较完整颈椎运动功能单位稳定。结论:纯钛颈椎植骨融合器适用于前路间盘摘除减压手术的椎间固定融合,尤其是多节段病变的病例。

AIM: To compare the biomechanical stiffness of a standard method of anterior cervical interbody fusion using bone graft with the same procedure using a new titanium threaded fusion cage. METHOD: In vitro biomechanical testing was performed on twelve cervical human spines. They were subjected to flexion-extension, bilateral bend, axial torque and axial compression while displacement was measured. Stiffness was calculated from the load-displacement curves for each direction under each load pattern. RESULTS: The anterior cervical interbody fusion by bone graft alone was the least stable construct of all modes tested, and the titanium threaded fusion cage implantation is stabler than the intact cervical sample. CONCLUSION: The titanium threaded fusion cage can be used in anterior intervertebral fusion, especially in the case of multi-segmental degenerative lesion.