摘要
目的探讨口腔颌面颈部较为罕见的淋巴组织增生疾病Castleman's Disease(CD)的临床病理特点、诊断及治疗预后。方法收集2007年至2017年间就诊于南京医科大学附属口腔医院、病理确诊为口腔颌面颈部CD的患者,分析相关临床病理特征和随访资料。结果本文共收集了6例口腔颌面颈部CD患者,临床表现均为单个渐大无痛性肿物;所有患者均行手术切除治疗;术后病理诊断均为透明血管型CD (hyaline-vascular CD,HVCD);随访2个月至9年余,均无肿物复发。结论口腔颌面颈部Castleman病较为罕见,确诊依赖病理,临床上以单中心型CD(unicentric CD,UCD)多见,治疗主要是手术切除,总体预后良好。
Objective To summarize the clinical,pathological characteristics and treatment of Castleman's disease(CD)in oral,maxillofacial and neck region.Methods The CD cases in oral maxillofacial and neck region treated in Affiliated Stomatological Hospital,Nanjing Medical University from 2007 to 2017 were identified.The relevant clinicopathological and follow-up data were collected and presented.Results Six cases of CD were identified withthe histopathological subtype as hyaline-vascular type.Surgical resection of these masses was performed in all cases.No evidence of disease recurrence was found during the follow-up ranging from 2 months to 9 years.Conclusions Castleman disease rarely occurs in oral,maxillofacial and neck region and its diagnosis relies on pathological examination.Surgical resection is a primary treatment with favorable prognosis.
作者
何小桐
王琼
吴亚平
王东苗
王琰玲
程杰
HE Xiaotong;WANG Qiong;WU Yaping;WANG Dongmiao;WANG Yanling;CHENG Jie(Department of Oral and Maxillofacial Surgery,Changzhou Stomatology Hospital,Changzhou 213003 China)
出处
《口腔医学》
CAS
2019年第3期246-249,共4页
Stomatology
基金
江苏省青年医学人才培养对象(QNRC2016851)
江苏高校优势学科(2014-37)
关键词
CASTLEMAN病
头颈部
临床表现
诊断
预后
Castleman’s Disease
head and neck
clinical presentation
diagnosis
prognosis
