牙周健康状况与男性不育症相关性的研究进展

Research progress of relationship between periodontal condition and male infertility

口腔健康与人体全身健康密切相关。牙周病是一种发生于牙周支持组织的口腔感染性疾病,与多种全身系统性疾病存在相关性。研究表明男性不育症与口腔疾病、特别是牙周病可能存在关联。然而,其作用机制尚未明确,目前存在两种假说,其一为牙周细菌慢性感染,其二为细胞因子的作用。本文主要就牙周疾病与男性不育症相关性及其可能作用机制进行综述。

Oral health is closely related to general health.Periodontal disease,an oral infectious disease occurring at periodontal tissues,might be related to some systemic diseases.Some studies show that male infertility might be related to some oral diseases,especially to periodontal diseases.However,its mechanism of action remains uncertain and there are two hypotheses supporting this association,namely,the chronic infection of periodontal bacteria and the effect of cytokines.This article aims to review the association between periodontal condition and male infertility and the possible mechanism of the action.