脱矿牙本质基质材料在颌骨骨缺损修复的应用

Application of demineralized dentin matrix material in the reconstruction of jaw bone defect

颌骨缺损会导致颌面部的功能及形态的异常。所以术后的骨缺损修复是必要的。为了避免自体骨移植所带来的二次创伤,寻找优良的骨替代材料是目前的研究热点。牙本质材料因为其易获取,制备简单,成骨效果良好而获得许多关注。并且学者发现脱矿后的牙本质成骨能力更为显著。该文将对脱矿牙本质材料的成骨基质及临床应用作一综述。

Jaw bone defects are common in oral maxillofacial surgery,which will lead to abnormality in the function and morphology of maxillofacial region.So bone defect repair is necessary.To avoid secondary injury caused by autogenous bone harvesting,seeking an ideal bone substitute material becomes the present research focus.Dentine material has been paid much attention in recent years because of its similar characteristics to bone and merits of easy availability,simple preparation and good ability to form new bone.Researchers found that decalcification makes dentine material a more effective material which can help bone formation.This paper reviewed the characteristics,mechanism of bone formation and clinical application of decalcified dentin matrix.