局麻加用右美托咪定在乳腺肿块切除术中的临床观察

Clinical observation of dexmedetomidine for excision of breast mass under local anesthesia

目的:探讨在乳腺肿块切除术局麻下加用盐酸右美托咪定的临床疗效。方法:选取我院2013-01~2013-06共40例乳腺肿块患者,按随机数字表分为右美组及盐水组各20例,右美组局麻下加用右美托咪定干预,盐水组为局麻下予生理盐水安慰剂干预,对比两组患者间临床疗效差异性。结果:右美组较盐水组镇静镇痛效果好,利多卡因用量少,住院时间短,血压、心率波动幅度小。结论:右美托咪定在局麻下乳腺肿块切除术患者中应用镇静镇痛安全,易唤醒,无呼吸抑制,并减少局麻药量,效果理想。

Objective:To explore the clinical efficacy of breast mass patients under local anesthesia with dexmedetomidine.Methods:40cases of breast mass patients in our hospital from January 2013 to June2013were chosen and randomly divided into experimental group and control group with 20 cases in each group.The patients under local anesthesia were intervened with dexmedetomidine in experimental group,while the patients under local anesthesia were intervened with saline placebo in control group.The clinical data differences between two groups' patients were compared.Results:The sedative effect in the experimental group was better than that in control group.As for experimental group,the dosage of lidocaine was smaller;the hospitalization time was shorter;and blood pressure and heart rate fluctuation amplitude was smaller.Conclusion:Dexmedetomidine was safe for the excision of breast mass patients under local anesthesia.It was easy to waken patients and no respiratory depression was found.It could also reduce the amount of local anesthetics.All in all,the effect was ideal.