从“重启慢性疲劳综合征研究”受关注谈起

Discussion based on the popularity of “A reboot for chronic fatigue syndrome research”

'疲劳'是中医最为重视的名词之一,中医学认为它与各种疾病如影随形,是中医'辨证'中需提取或排除的一个重要的症状要素,也一直为我们所关注.Nature于2018年公布了最受关注的十大科学长篇专题报道,其一主题为'重启慢性疲劳综合征研究'(Areboot for chronic fatigue syndrome research)[1].

Chronic fatigue syndrome(CFS)has been more than 30 years since its concept came into being,with nearly 70 years related research.Different countries have proposed different diagnostic criteria at different times.This is a research field overwhelmed with twists and controversy.At present day,there is no convincing conclusion to satisfy everyone,and the detrimental effect of this disease continuing to rise.'Fatigue'has always been the center of attention,as it is one of the keywords in traditional Chinese medicine.Traditional Chinese medicine believes that fatigue is a comorbidity of many different diseases,hence an important factor in the clinical diagnosis of traditional Chinese medicine.From a professional perspective,it is not difficult to see that the biggest obstacle to the development of ME/CFS research lies in its vague boundary/scope and unclear concept.Therefore,in 2015,the National Institute of Medical Sciences proposed to reinitiate the study,and suggested renaming it as Systemic Exertion Intolerance Disease(SEID)and putting forward new diagnostic criteria.The updated SEID concept focuses on'deep fatigue'and reduces interactions with other diseases.In 2018,Nature published a long featured report,'A reboot for chronic fatigue syndrome research'.The report became the buzz topic of the year.These actions may prompt new in-depth studies for this research.This paper combs through the cognitive changing process of chronic fatigue syndrome,and provides a positive response from reviewing the different perspectives of traditional Chinese medicine and Western medicine,reanalyzing the previous research in this field,to assess the possibility of incorporation of traditional Chinese medicine,and utilization of traditional Chinese medicine knowledge-based reference,and to put forward new insights as well as potential obstacles in the'reboot'study.Based on the theoretical analysis and the conclusion of our previous research,we believe that:after the clear diagnosis of SEID(or CFS),the influence of psychosocial factors should be taken into account when conducting intervention or in-depth research.In scientific research,this may lead to the solution of some of the problems.Clinically,this may enhance the body’s psycho-physical harmonization and will help improve patient condition and the curative effect.Previous practice has shown that,the deep involvement of traditional Chinese medicine the reboot of this grand international project will help SEID patients to improve their self-perception and symptoms,and its role in the scientific mechanism will be conducive to promoting the systematization and deepening of research.