母儿血型不合IgG抗体效价≥1∶512是否提示胎儿病情严重

Whether Fetus Would be Ominous in Blood Group Incompatibility If IgG Antibody's Efficiency More than 1∶512

目的 探讨母儿血型不合 Ig G抗体效价≥ 1∶ 5 12是否提示胎儿病情严重。 方法 对6例血清 Ig G抗 A(B)抗体效价≥ 1∶ 5 12的母儿血型不合孕妇 ,进行羊膜腔穿刺抽取羊水作胆红素、Ig G抗体效价和胎儿血型物质测定 ,抽取其新生儿脐血作胎儿血型、胆红素检测及 Coom bs试验。 结果 孕妇血清 Ig G抗体效价与新生儿溶血病的严重程度并不密切相关。

Objective To investigate the fetal haemolytic status when IgG antibody's efficiency of pregnant women was ≥1∶512 in blood group incompatibility. Methods We retrospectively analyzed the data of 6 pregnant women whose IgG antibody's efficiency were more than 1∶512 in blood group incompatibility. The levels of bilirubin, IgG antibody's efficiency and blood type in amniotic fluid from amniocentesis were examined. Umbilical blood bilirubin, blood type analysis and Coombs test of newborns were performed. Results Serum IgG antibody's efficiency of pregnant women did not correlate with the severity of haemolytic disease of newborn. Conclusions Fetal haemolytic disease can not be diagnosed only by serum IgG antibody's efficiency of pregnant women.