布地奈德气雾剂治疗儿童哮喘临床观察

Observation of effects of budesonide inhaler in the treatment of childhood asthma

目的:观察布地奈德(普米克)气雾剂治疗儿童哮喘的临床疗效。方法:首次吸入最小剂量为200μg/d,最大剂量800μg/d,喘息控制后,在短期内减至200～400μg/d,以后根据临床症状、最高呼气峰流速值(PEF),布地奈德逐渐减至最小维持剂量。结果:治疗后与治疗前相比,经成组t检验,P均<0.01,PEF％均有明显上升。结论:布地奈德气雾剂治疗儿童哮喘安全有效,方法简便。

Objective: To assess the efficacy and safety of budesonide inhaler in the treatment of childhood asthma. Methods: Initial administration dose of budesonide inhalation (mininum 200 μg/d, maximum 800 μg/d) is suggested. After the asthma controlled, the dose reduced to 200 - 400 μg/d, and then based on clinical manifestation and peak expiratory flow (PEK), budesonide can be gradually reduced to minimum maintenance dose. Results: At the end of treatment the PEK apparently rose up, group t test indicated statistic significance, P < 0. 01. Conclusion: Budesonide inhaler in the treatment of childhood asthma is effective and safe as well as simple.