静脉注射丙种球蛋白防治早产儿感染临床观察

Clinic observation on the treatment of infection of premature babies with intravenous injection of gammaglobulin

目的:探讨静脉应用丙种球蛋白(IVIG)在防治早产儿感染中的临床价值。方法:随机将82例早产儿感染病例分为IVIG治疗组和常规治疗组,IVIG组在常规治疗基础上早期应用静脉丙球500mg/kg稀释成25ml静滴,使用2～3次。结果:IVIG在改善一般状况、缓解症状、控制感染病灶、缩短住院时间和提高治愈率方面均优于常规治疗,且无明显副作用。结论:早产儿感染性疾病在应用抗生素的同时,早期应用IVIG可增强患儿免疫功能,降低病死率。

Objective: To assess the clinical value of gamma globulin in the vein application in preventing and curing infections in premature babies. Method: Divide the 82 cases at random into IVIG group and control group. Besides the normal treatment, IVIC group had got additional intravenous drip with the dilution of 25 ml from IVIG at 500 mg/kg 2 to 3 times. Results: Curative effects of IVIG group are obviously better in their general condition, alleviating the symptoms, controlling focus of infection, shortening the time of hospitalization and improving the curative rate, and no obvious side-effect was observed. Conclusion: The infectious disease of the premature babies in earlier period should be treated with IVIG method along with the antibiotics, hence, to strengthen the immunity functions of the sick infants and lower the death rate.