Brugada综合征
摘要
Brugada综合征是指具有反复发生心室颤动危险的一组病人，此组病人多无器质性心脏病，心电图表现为右束支传导阻滞和右胸导联上ST段抬高。此综合征是钠通道α亚单位遗传缺陷所致，该缺陷引起钠内流减少，心外膜动作电位切迹更加明显，从而使ST段更加抬高。钠通道阻滞剂可强化这些临床表现，并用于筛选间歇性出现心电图变化的病人。这些病人预后较差，有症状的病人需要安装ICD治疗。
出处
《世界医学杂志》
2003年第2期23-26,共4页
International Journal of Medicine
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