放射性核素显像诊断和瘤内注射治疗肢体血管瘤

Characterization and Treatment of Hemangioma of Limbs using Radionuclide Imaging and Interstitial Injection of ^(32)P-colloid

目的 :探讨放射性核素血流、血池显像显示肢体血管瘤的结构与功能特点。材料和方法 :10 7例肢体血管瘤分布于四肢不同部位。以99mTc体内法标记自体红细胞 (RBC)行肢体动脉或静脉动态显像 ,加肢体血池静态显像。根据显像表现 ,99例接受32 P胶体瘤内注射治疗 ,并与 2 5例手术结果对比研究。结果 :所有病灶均表现为血池显像持续性浓聚 ;11例动脉相、10例静脉相病灶早期充盈 ;39例静脉充盈延迟 ;2 9例可见病灶与异常血管相连 ;49例主病灶周围可见卫星病灶。瘤内核素注射治疗后 ,6 4例显效 ,35例病灶缩小 ;手术治疗后复发病灶核素治疗有效。结论 :核素显像和瘤内注射可以反映和治疗不同亚型的肢体血管瘤。

Purpose: Radionuclide was employed for the evaluation and treatment of the soft-tissue hemangioma on limbs. Materials and Methods: 107 patients with hemangioma on their limbs were studied using in-vivo labeled 99mTc-RBC. Both dynamic and static imaging were undertaken at the sick limb. 99 cases were also received an intratumoral injection of 32P-colloid according to the scintigraphic findings, and 25 cases undergoing surgery were comparatively analyzed too. Results: All lesions were shown high concentration of the radiotracer at static blood pool imaging, while 11 and 10 showed accelerated accumulation at arterial and venous phase respectively; 39 lesions had slow filling of affected veins, and 29 with abnormal blood vessels; 49 had satellite foci outside the main lesions. After interstitial therapy, 64 lesion responded significantly, and 35 had partial response. The lesion having failed surgery responded to 32P. Conclusion: radionuclide imaging and treatment is feasible in characterizing and treating the soft tissue hemangioma at extremities.