结直肠癌所致血小板增多及其关系探讨

Thrombocythemia in Patients with Colorectal Cancer and the Interaction of Platelet and Metastasis

目的 :探讨结直肠癌所致血小板增多及其与肿瘤转移的相互关系。方法 :检测结直肠癌患者治疗前、治疗后、复发和转移各组的血小板数 ,并与正常人比较。结果 :结直肠癌治疗前组、复发组和转移组与对照组比较 ,血小板数增多 ,血小板数有随结直肠癌病程进展而增多的倾向 ;有效治疗后 ,血小板数降低和恢复正常。结论 :血小板与结直肠癌的发展、复发和转移有关 。

Objective To explore thrombocytosis in patients with colorectal cancer and the interaction of platelet and tumor metastasis.Method Platelet counts were detected respectively in patients with colorectal cancer in pre-treatment,post-treatment,relapse and metastasis and compared with health people as control.Results Platelet counts of patients with colorectal cancer in pre-treatment group,relapse group and metastasis group were increased comparing with control,and following course development, platelet counts were also increased.Platelet counts were decreased in patients with colorectal cancer after efficacious therapy.Conclusions There is a close relationship between platelet and colorectal cancer. Thrombocytosis can be used as an efficacious and prognostic reference indication in patients with colorectal cancer.