胃肠道症状与糖尿病关系的分析

Diabetes Mellitus and Its Gastrointestinal Symptoms

目的:通过对因糖尿病住院患者的胃肠道症状观察,了解糖尿病胃肠道症状的特点。方法:收集1986年1月～1997年4月间于我院住院治疗的674例糖尿病患者的相关临床资料,分析糖尿病患者胃肠道症状的发生率及其临床特点。结果:224例糖尿病患者出现一项或一项以上的胃肠道症状,以腹胀、恶心、呕吐、腹泻及便秘为主。1型糖尿病患者胃肠道症状与疾病病程无关,2型糖尿病患者病程与胃肠道症状发生成正比。有胃肠道症状组空腹血糖显著高于无症状组,而糖化血红蛋白水平在两组无差异。有胃肠道症状组糖尿病患者神经病变、糖尿病肾病及视网膜病变发生率显著高于无症状组患者。结论:33.2％糖尿病患者存在胃肠道症状,以腹胀、恶心、呕吐、腹泻及便秘为主,1型糖尿病、病程长于10年、空腹血糖高及存在糖尿病慢性合并症的患者胃肠道症状发生几率大,应引起重视。

Objective/Methods: To evaluate the gastrointestinal symptoms of the in - patients diabetes mellitus, 674 in-patients diabetes mellitus patients from January 1986 to April 1997 were studied retrospectively. Results: 224 diabetic patients suffered from one or more gastrointestinal symptoms, such as abdominal distension, nausea, vomiting, diarrhea and constipation. Of type 2 diabetes mellitus patients, the long course group( ≥10 years) had significantly higher incidence of gastrointestinal symptoms compared with the short course group ( < 10 years) .The gastrointestinal symptoms had no relation with the course of type 1 diabetes mellitus. The fasting blood glucose levels of the gastrointestinal symptom group were significandy higher than those of the non - gastrointestinal symptom group, but the glycosylated hemoglobin levels were similar in two groups. The patients with gastrointestinal symptoms also had significantly higher incidence of diabetic neuropathy, nephropathy and retinopathy compared with the patients without gastrointestinal symptoms. Conclusion: Abdominal distension, nausea, vomiting, diarrhea and constipation are common in diabetic patients. Type 1 diabetes mellitus, the course longer than ten years, high fasting blood glucose level and other diabetic chronic complications, indicated the higher incidence of gastrointestinal symptoms.