摘要
目的:通过快速床旁检测急性心肌梗死(Acute myocardial infarction,AMI)患者和不稳定心绞痛(Unstable angina,UA)患者血浆中BNP浓度,对比研究BNP对AMI患者危险分层及预后评价的价值。方法:入选2002年7月～2003年2月的AMI和UA患者,分为AMI组和UA组。即刻床旁抽血行床边BNP和心肌酶三项(CK-MB、Myo、TNI)的快速测定。同时观察入院时血压、心率、肺部罗音和住院期间及出院后一个月内不良事件。结果:入选AMI患者25例和UA20例。其中AMI组肺部有湿性罗音组12例和无罗音组13例。AMI组和UA组的BNP、肺部罗音和不良事件分别为(376.9±410.2)pg/ml和(45.2±20.6)pg/ml(P<0.001)、12例和4例、不良事件3例和0。有湿性罗音组和无罗音组的BNP浓度分别为(604.8±425.2)pg/ml和(149.1±81.5)pg/ml(P<0.05)、年龄分别为(71.1±13.5)岁和(61.7±11.2)岁(P<0.05)、不良事件分别为3例和0例,而两组间Myo、CPK-MB、TNI无差异性。结论:快速床旁检测AMI患者血浆中BNP浓度有助于对AMI患者进行危险分层和评价预后。
Objective: To assess the value of rapid bedside measurements of BNP on risk stratification and prognosis in patients with AMI and UA. Methods: To enroll patients with AMI and UA from 2002.7 - 2003.2 and were grouped AMI and UA. The rapid bedside measurements of BNP,CK - MB,Myo and TNI were performed. While the patients'blood pressure,heart rate , pulmonary rales and adverse cardiac events were recognized.Results: 25 patients with AMI and 20 patients with UA were enrolled. 12 patients with AMI have pulmonary rales and 13 patients without. BNP,pulmonary rales and adverse cardiac events were (376.9± 410.2)pg/ ml and (45.2± 20.6)pg/ml, 12 cases and 4 cases,3 cases and 0 in group AMI and group UA,respectively. BNP (604.8 ± 425.2) pg/ml and (149.1 ± 81.5)pg/ml(P < 0.05) ,ages were (71.1 ± 13.5)y and (61.7± 11.2)y in patients with pulmonary rales and without, respectively. Conclusion: The rapid bedside measurements of BNP can help to evaluate the risk stratification and prognosis in patients with AMI.
出处
《中国医药导刊》
2003年第2期114-115,共2页
Chinese Journal of Medicinal Guide
