三种结核抗体诊断试剂盒对结核病的诊断价值

Value of three kinds of tuberculous antibody in diagnosis of tuberculosis

目的探讨三种结核抗体诊断试剂盒对肺结核的诊断价值。方法采用加拿大产RapidTestTB、澳大利亚TB-DOT、国产LANBO试剂盒检测135例肺结核病人血清,50例非结核肺部疾病,40例健康人血清的结核抗体对比观察。结果三种结核抗体敏感性RAPIDTestTB为62.2%,TB-DOT为83.7%,LANBO为86.7%,特异性分别为97.5%、87.5%、92.5%、RapidTestTB与TB-DOT、LANBO法比较敏感性有显著性差异(P<0.05)。结论三种结核抗体盒中以RapidTestTB特异性高、敏感性低,TB-DOTLANBO敏感性高,特异性偏低,诊断肺结核时,最好先用二种或二种以上试剂进行测定。

Objective To study the value of three kinds of tuberculous antibody in diagnosis of pulmonary tuberculosis.Methods Ttuberculous antibodies in serum of135patients with pulmonary tuberculosis,50cases of non-tuberculosis and40healthy individuals were detected using Rapid Test TB produced by Canada,TB-DOT produced by Australia and homemade LANBO.Results The sensitivities were62.2%?83.7%?86.7%and the specificity were97.5%?87.5%?92.5%respectively.The sensitivity of Rapid Test TB was significant difference comparing to TB-DOT and LANBO (P<0.05).Con clu sion In three kinds of tuberculous antibody,the specificity of Rapid Test TB is higher and the sensitivity is lower than those of TB-DOT and LANBO.The results sug-gested that detection of tuberculous antibody in serum is useful for diagnosis of pul-monary tuberculosis by selecting two or more reagents.