联机清除率监测器在复用透析器效果监测中的作用评价

Assessment of the role of online clearance-rate monitor on monitoring the effect of reused dialyser

目的 对联机清除率监测器 (OCM)在复用透析器效果监测中的作用进行评价。方法 2 0例接受血液透析患者 ,分别在透析器首次使用和复用第 5次时用OCM和常规取血法测定尿毒清除指数 (Kt/V) ,同时测定总透析器容量 (TCV)。结果 透析器首次使用与复用第 5次时 ,OCM和常规取血法测定Kt/V值均差异无显著性 (P >0 0 5 ) ,而且两种方法的Kt/V测定结果直线相关分析均有显著意义 (P <0 0 1) ;TCV测定结果与OCM法和常规取血法Kt/V测定结果直线相关分析均无显著意义 (P >0 0 5 )。结论 OCM法监测复用透析器的Kt/V使用方便、效果可靠 ,可代替常规取血法Kt/V测定 ;TCV测定不能准确反映Kt/V 。

Objective To assess the role of online clearance rate monitor(OCM) on monitoring the effect of reused dialyser.M20 patients on hemodialysis were recruited in this study.Urea clearance index (Kt/V) was measured by the methods of OCM and traditional blood analysis on the first time used dialyser and the fifth time used dialyser respectively,while total column volume(TCV) was also determined.Results For either the first time used dialyser or the firth time used one,there was no sigificant difference between the OCM results and blood analysis results(P>0 05),while there was significant linear correlation between the two Kt/V detection methods(P<0 01).For the fifth time used dialyser,there was no significant correlation between TCV and OCMs Kt/V (P>0 05),nor between TCV and blood analysiss Kt/V. Conclusion OCM can be used to monitor Kt/V of reused dialyser conveniently and reliably,with the possibility to replace blood analysis.TCV cant reflect Kt/V accureately,so it cant act as the sole index of the monitoring effect of reused dialyser. [