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阻断内毒素信号传导通路治疗脓毒症或脓毒性休克的研究进展 被引量:12

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出处 《中华急诊医学杂志》 CAS CSCD 2003年第2期135-137,共3页 Chinese Journal of Emergency Medicine
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参考文献10

  • 1Hoshino K,Takeuchi O,Kawai T,et al.Cutting edge: Toll - like receptor 4 ( TLR4 ) - dificient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS gene product[].J immunol.1999
  • 2Onishi HR,Pelak BA,Gerckens LS,et al.Antibacterial agents that inhibit lipid A biosynthesis[].Science.1996
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  • 5Bunnel E,Lynn M,Habet K,et al.A Lipid A analog, E5531, blocks the endotoxin response in human volunteers with experimental endotoxemia[].Critical Care Medicine.2000
  • 6Chow JC,Young DW,Goleubock DT,et al.Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction[].Journal of Biological Chemistry.1999
  • 7Gudmundsson GH,Agerberth B,Odeberg J,et al.The human gene FALL39and processing of the Cathilin precursor to the antibacterial peptide LL-37 in granulocytes[].European Journal of Biochemistry.1996
  • 8Haas CJ,Zee R,Benaissa-Trouw B,et al.Lipopolysaccharide (LBS) -bingding synthetic peptides derived from serum amyloid P component neuftralize LPS[].Infection and Immunity.1999
  • 9Le Roy D,Di Padova F,Tees R,et al.Monoclonal antibodies to murine lipopolysaccharide ( LPS)-binding protein ( LBP) protect mice from lethal endotoxemia by blocking either the binding of LPS to LBP or the presentation of LPS/LBP complexes to CD14[].J Immunol.1999
  • 10Giroir BP,Scannon PJ,Levin M.Bactericidal/permeability increasing proteinlessons learned from phase Ⅲ, randomized,clinical trial of rBP121 for adjunctive treatmemt of children with severe menigococcemia[].Critical Care Medicine.2001

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