亚甲蓝与中性及电荷型β-环糊精的包合特性

Inclusion Behavior between Methylene Blue and Neutral or Charged β-Cyclodextrins

采用荧光光谱法研究了亚甲蓝与中性及电荷型 β 环糊精衍生物的包合特性。结果表明 :主 客包合物的化学计量关系为 1∶1 ,以包合常数作为包合作用的量度 ,则在中性和碱性条件下包合能力呈羧甲基 β 环糊精 >羟丙基 β环糊精 >β 环糊精 ;电荷型β 环糊精除了通常的疏水作用为包合驱动力外 。

The inclusion properties of methylene blue and neutral or charged β-cyclodextrins were studied by using fluorimetric method.The results show that stoichiometry of host-guest is 1∶1 and binding capacity is CM-β-CD>HP-β-CD>β-CD.There exists not only hydrophobic interaction but also electrostatic interaction between host and ionic guest molecule.