肿瘤患者深部真菌医院感染现状调查

Status of Hospital Deep Fungus Infection in Tumor Patients

目的 调查肿瘤患者深部真菌医院感染现状 ,以制定有效的防治措施。方法 收集本院 2 4 6例肿瘤患者的临床资料及真菌培养结果 ,加以统计和分析。结果 2 4 6例感染部位以下呼吸道为主 (46 .9% ) ,泌尿道次之(2 1 4 % ) ,2 4 6例患者标本共培养出真菌 2 4 6株 ,以白色假丝酵母菌占第 1位 (5 8.1% ) ,热带假丝酵母菌占第 2位(2 4 .8% )。结论 本组病例发生真菌医院感染的病因与原发肿瘤疾病、年龄、手术及放射疗法、免疫抑制剂和激素、抗代谢药物的使用、抗生素的使用及住院期间侵入性操作等危险因素密切相关。

OBJECTIVE To investigate current status of hospital deep fungus infection in tumor patients. METHODS The clinical data and fungus culture results of 246 tumor patients were collected and analyzed. RESULTS Among 246 cases the infection occurred predominantly in lower respiratory tract (46.9%), and with urological tract being second (21.4%). Of 246 strains of fungus from 246 patients, the first was Candida albicans (58 1%), the second was C. tropicalis (24.8%). CONCLUSIONS The causes of hospital deep fungus infection in tumor patients were highly associated with risk factors such as primary tumor disease, age, operation and radiological therapy, the application of immune inhibitor, hormone, anti metabolism drugs and antibiotics, invasive operation, and so on.