肠球菌属细菌的临床分布及耐药性分析

Analysis on clinical distribution and drug resistance of Enterococcus spp

目的 分析我院肠球菌属在临床标本中的分布 (临床分布 )及耐药状况。方法 应用Sensititre全自动细菌鉴定系统鉴定菌种 ;用纸片扩散法和Etest法进行药敏试验。结果 肠球菌分离率分别为尿液 38%、脓汁 19%、痰液 14 %、引流液 10 %、其他标本 19%。 91株肠球菌中粪肠球菌 6 7%、屎肠球菌 32 %、坚忍肠球菌 1%。粪肠球菌和屎肠球菌庆大霉素高耐株达 5 0 %以上。屎肠球菌对 β 内酰胺类抗生素的耐药率明显高于粪肠球菌 ,未发现万古霉素耐药株 ,但有两株Etest法呈中介水平。结论 肠球菌在我院临床标本中分布较广 ,以粪肠球菌和屎肠球菌为主 ;除对万古霉素敏感外 。

Objective To study distribution and drug resistance of Enterococcus spp in our hospital.Methods Enterococci were identified by Sensititre Microbiology System. The antimicrobial susceptibility was tested by using agar dilution method and Etest. Results Enterococci were isolated from urine(38%),pus(19%),sputum(14%),abdominal drainage(10%) and other specimens(19%), respectively.There were 67% E.faecalis, 32% E.Faecium and 1%E.durans among ninety one strains of enterococci.There were more than 50% E.faecalis and E.Faecium which were resistance to high level gentamicins.Resistant rate to β Lactams of E.Faecium was higher than E.faecalis .The strains of resistance to vancomycin were not found but two strains of intermediate to vancomycin were detected by Etest.Conclusion Enterococci distribute to clinical specimens widely. E.faecalis and E.Faecium are the most species.Most of them were resistant to many kind of antimicrobial agents except vancomycin.