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慢性肝病血清瘦素水平测定 被引量:11

Measuring the level of serum lepin in chronic liver disease.
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摘要 为了解慢性肝炎、脂肪肝、肝硬化患者血清瘦素水平情况,选择慢性肝炎17例,脂肪肝、肝硬化、正常对照各21例,分别测量受试者的身高、体重,计算体重指数(BMI)、体脂肪含量(%Fat),血清瘦素水平采用酶联免疫吸附试验(EusA)的方法测定,并进行结果分析。结果显示:肝炎组、脂肪肝组瘦素水平明显高于对照组;肝硬化组与对照组无差异,血清瘦素水平与肝功能分级无关;丙型肝炎病毒所致的肝病血清瘦素水平与对照组相比差异不显著。上述说明瘦素与多数慢性肝病有关。 To determine the possible clinical significance of the serum leptin through estimating its levels in chronic hepatitis, fatty liver and cirrhosis of liver. 21 patients with fatty liver, 21 patients with cirrhosis of liver and 21 normal persons were admitted to the investigations: the height and weight of the candidates were measured simultaneously, body mass index and percent of body fat were calculated. The level of leptin was measured by ELISA. We found that the level of leptin from hepatitis and fatty liver is significantly higher than that of the control; there is no difference between the cirrhosis of liver and the control and no difference between male and female in cirrhosis of liver, no difference was found between the level of leptin and the stratification of the liver function. The level of leptin from hepatitis C is not related to that of the control. Leptin is related to a lot of chronic hepatitis.
出处 《临床肝胆病杂志》 CAS 北大核心 2003年第1期25-26,共2页 Journal of Clinical Hepatology
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