410例药疹临床分析

Clinical analysis of 410 cases of drug eruption

通过对410例药疹临床分析,发现最常见致敏药物分别为头孢菌素和氨苄青霉素类、解热镇痛类、狂犬疫苗、磺胺类和四环素类等,表现多为猩红热样型、麻疹样型、荨麻疹型及粘膜水肿或溃烂型。

An clinical analysis was conducted among a cohort of 410 patients drug eruption with treated in our department from January 1995 to December 2001. We found that the common drugs likely to lead to anaphylactic reactions included cephalosporins, ampicillin types, antipyretic analgesic types, rabies vaccine, sulfonamides, tetracyclines types, etc. The drug eruption mostly presents diverse clinical features resembling the rashes as seen in cases of scarlet fever, measles, urtica, or mucosal edema or ulceration.