p53基因在膀胱肿瘤中的研究进展

Progress in research on p53 gene in bladder cancer

p5 3基因与膀胱肿瘤相关性研究很多 ,绝大多数研究认为p5 3的突变与膀胱肿瘤的发生有关。为对其做进一步深入研究 ,本文综述了近 3年有关化学致癌物质引起p5 3基因突变机制、p5

A lot of researches on the relationship between p53 gene and bladder cancer have been reported and most of their results suggested that mutation of p53 gene was frequently found in bladder cancer.In order to further understand the progress in it,researches on the mechanism of mutation of p53 gene caused by chemical carcinogen,molecular biological behavior of p53 gene,as well as its application in gene therapy for bladder cancer during the recent three years were reviewed in this article.