组织工程软骨种子细胞的研究进展

ADVANCE ON SEED CELLS OF TISSUE ENGINEERING CARTILAGE

目的 综述组织工程软骨种子细胞及培养系统的发展近况。 方法 广泛查阅近年来有关组织工程软骨种子细胞和培养系统的文献 ,进行综述。 结果 回顾了组织工程软骨的种子细胞来源及培养方法 ,自体或异体软骨细胞仍然是目前软骨组织工程的主要细胞 ,三维立体细胞培养体系是现在主要的细胞培养体系。 结论 组织工程软骨种子细胞的来源有待于进一步发掘 ,培养体系有待于进一步完善和发展。

Objective To sum up the research advances of the seed cell and the culture system using in tissue engineering cartilage. Methods The recent original articles about the seed cell and the culture system in tissue engineering cartilage were extensively reviewed. Results At present, autologous or homologous cells is still major seed cell and the three dimensional culture system is also major system for tissue engineering cartilage. Conclusion The source of seed cell for tissue engineering cartilage should be further explored, and the culture system need to be improved and developed.