摘要
肾素-血管紧张素-醛固酮系统(renin-angiotensin system,RAS)基因是一种激素内分泌系统,在心血管功能调节、水盐平衡调节中起重要作用。RAS基因是妊高征主要的致病基因。AGT基因M235T多态、AT1R基因A1166C多态、ACE基因I/D缺失多态与妊高征的发病相关。
Renin-angiotension system is a hormone-endocrine system. It plays an important role in the regulation of cardiovascular function and sodium and water homeostasis. RAS genes are the capital virulence genes of preeclampsia. An insertion/deletion ( I/D ) polymorphism of an-giotensin-converting enzyme (ACE) gene, M235T variants of angiotensinogen (AGT ) gene and A1166C polymorphism of angiotensin Ⅱ type 1 receptor gene are associated with preeclampsia.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2003年第1期46-49,共4页
Reproduction and Contraception
