高精度散射光度滴定法测定复方氯化钠注射液中氯化钾的含量

Determination of potassium chloride in Compound sodium chloride injection with highly-accurate nephelometric titrimetry

目的 研究复方氯化钠注射液中氯化钾的含量测定新方法。方法 用高精度散射光度滴定法代替四苯硼钠重量法。结果 高精度散射光度滴定法重复性好 (RSD =0 .17% ,n =6 ) ;准确度高 ,平均回收率为 99.5 6 % ;与重量法所测定样品结果基本一致。结论 所用方法准确、便捷 。

OBJECTIVE To build up a method for the determination of potassium chloride in Compound sodium chloride injection. METHODS Sodium tetraphenylboron gravimetric analysis was replaced by highly-accurate nephelometric titrimetry to determine potassium chloride in Compound sodium chloride injection. RESULTS The repeatability( RSD =0.1672%, n =6)and recovery(99.56%)were all perfect. CONCLUSION It provided a suitable method to determine the contents of potassium chloride in Compound sodium chloride injection.