夜交藤抗炎抑菌作用的实验研究

Anti-inflammatory and bacteria inhibition effects of-Caulis Polygoni Multiflori

目的 研究夜交藤的抗炎抑菌作用。方法 采用药理实验方法 ,观察体外抑菌和对二甲苯致小鼠耳肿胀的急性炎症及大鼠棉球肉芽肿的慢性炎症的影响。结果 夜交藤对慢性炎症有明显的抗炎作用 ,而无抗急性炎症的作用 ;对金色葡萄球菌、大肠杆菌、肺炎链球菌、卡他萘瑟氏球菌、流感嗜血杆菌、普通变形菌有抑制作用。结论 可开发夜交藤抗慢性炎症的药物。

OBJECTIVE To study antibacterial and anti-inflammatory action of Caulis Ploygoni Multiflori . METHODS The acute inflammation models were established by daubing xylene to mice ear,which the chromic inflammation models were established by embedding cotton roll into rat's armpit. The action of antibacterial and anti inflammatory of Caulis Ploygoni Multiflori was observed by pharmacological method.RESULTS Caulis Ploygoni multiflori can obvious inhibit S. aureus,E .coli,β hemolytic streptococcus,S. pneumoniae, N. caviae, H.influenza,P. vulgaris and anti chronic inflammation, but has no effect to inhibit acute inflammation.CONCLUSION Caulis Ploygoni Multiflori may be used as an anti-chronic inflammatory drug.