艾滋病合并淋巴结结核病10例临床分析

Clinical treatment of AIDS patients with lymph node tuberculosis

目的 探讨艾滋病患者合并淋巴结结核病的临床治疗方法。方法 将 10例艾滋病合并淋巴结结核病患者分为抗痨治疗组 ( 5例 )和抗痨治疗 +抗逆转录病毒治疗 (HAART)组 ( 5例 ) ,并比较治疗前后CD4+ 细胞数的变化。结果 抗痨治疗 +HAART组CD4+ 细胞数明显上升 ,与抗痨治疗组比较 ,差异有显著性 (P <0 .0 5 )。结论 ( 1)CD4+ 细胞下降可能是艾滋病并发淋巴结结核病的主要原因 ;( 2 )艾滋病合并淋巴结结核病的患者合并症多 ,临床表现复杂多样 ,联合高效抗逆转录病毒治疗能缩短病程 ;( 3 )

Objective To explore the therapeutic procedure of AIDS with lymph node tuberculosis. Methods The data of 10 AIDS patients with lymph node tuberculosis diagnosed in You-An Hospital from 1995 to 2001 were retrospectively analyzed.Results Five patients were treated by anti-tuberculosis procedure combined with high efficiency anti reverse transcription virus therapy,other 5 patients simply by anti tuberculosis therapy.The remarkable rise of CD4 + cells was observed in the former group compared with the latter group( P <0.05).Conclusions (1) Decrease of CD4 + cells might be the main cause of lymph node tuberculosis in AIDS patients.(2) AIDS patients with lymph node tuberculosis usually have many complications and various clinical manifestations.They need long term treatment,high efficiency anti reverse transcription virus therapy might shorten duration of illness.(3) Old tuberculin test has no aid to diagnosis