肝癌间质及癌旁病变的病理分析

Clinical Significance of Pathological Changes in Interstitial and Peripheral Hepatocellular Carcinoma

目的 研究肝癌间质及癌旁病变的临床病理意义。方法 在 2 0例肝癌组织标本中取 45个癌结节 ,分别在癌结节中间、癌旁肝组织等部位取组织 4块 ,连续切片 ,显微镜下观察。结果 19个结节有完整窦内皮细胞围绕癌巢 ,其中癌结节肉眼小于3cm者 13个 ,大于 3cm者 6个。 2 6个癌结节无完整窦内皮细胞围绕癌巢 ,其中癌结节直径大于 3cm者 2 4个 ,小于 3cm者 2个。2 0例中有 13例合并肝硬化 ,17例有乙型肝炎病毒感染和HBsAg阳性。 结论 病理连续切片 。

Objective To study the clinical significance of pathological changes in interstitial and paracarcinoma tissue in hepatocellular carcinoma.Methods 45 nodes of carcinoma were obtained from 20 cases of hepatocellular carcinomas.4 pieces of tissues taken from central and paracarcinoma tissues of every node underwent serial sections and were observed with the microscope.Results In 45 carcinoma nodes,19 nodes had cancer rests completely surrounded by the endothelial cells of hepatic sinus,And the diameters were matter the than 3 cm in 13 nodes and greater in 6 nodes.The cancer rests were not completely surrounded in the other 26 nodes,of which 24 nodes were greater than 3 cm in diameter.Among the 20 cases,13 cases were with liver cirrhosis and 17 cases were with hepatitis B virus(HBsAg) infection.Conclusion Pathological changes in interstitial and paracarcinoma tissue in hepatocellular carcinoma are important for prognosis.