冠状动脉旁路移植术对冠心病的近期治疗效果

The early curative effect of coronary artery bypass grafting operation on coronary heart disease.

目的 :评价冠状动脉旁路移植术 (CABG)对冠心病的早期治疗效果。方法 :比较行CABG的冠心病患者 (实验组 ,n =75)术前、术后的心功能情况、EF值变化以及随访期内的冠心病死亡率、自主症状改善率和无症状生存率 ,并与未手术组 (对照组 ,n =10 0 )相应指标进行比较。结果 :实验组全部存活患者 ,术后自主症状明显改善 ,术后心功能级别 (NYHA分级 )及EF值均较术前明显提高 ,并有统计学意义 (P <0 0 5)。在1年的随访期内 ,两组同期因冠心病病死率实验组低 ,无症状生存率与生活质量的改善情况也较对照组有显著差异 (P <0 0 5)。结论 :冠状动脉旁路移植术 (CABG)是治疗冠心病心肌缺血的有效手段 ,对已有明显症状或已出现并发症的冠心病患者 ,早期治疗效果优于非手术记录。显著提高了患者的生存率与生活质量 ,对于其他治疗手段 (如PTCA)失败或出现紧急并发症者 ,CABG术成为改善心肌血运 。

Objective:To investigate the early curative effect of coronary artery bypass grafting(CABG)operation on coronary heart disease(CHD).Methods:Comparing the perioperative cardiac functional condition.The changes of EF value?the death rate of CHD patients in the follow-up survey stage\,the improvement rate of autonomous symptom and the survival rate of symptomless of the patients with CHD which were performed CABG operation(the experimental group,n=75),and comparing these indexes with the correspondence indexes of the patients without operation(the control group,n=100).Results:The postoperative autonomous symptom of all the survivor in the experimental group were improved obviously,the postoperative cardiac functional grading(NYHA grading)and the EF value were increased significantly,it had statistical value(P<0.05).During the follow-up survey stage(1 year),the death rate of CHD patients in the experimental group was lower than that in the control group,the survival rate of symptomless and the improvement condition of the quality of living were also different from that in the control group(P<0.05).Conclusions:The CABG operation was an effective method to cure myocardial ischemia,for the CHD patients with obvious symptom or complication,the early curative effect was better than the patients without operation,the survival rate and the quality of living were improved obviously;For the patients with emergency complication or treatment failure using the others therapy method(for example PTCA),the CABG operation was the only way to improve myocardial blood circulation and save patient′s life.