摘要
以2位烃基取代乙酸为起始原料,与烯丙基氯反应成酯后,在氢化钠的催化作用下进行Claisen重排反应得到4-戊烯酸类化合物,再经酯化和Claisen重排反应得到2-烃基-2,2-二烯丙基乙酸类化合物,4步反应收率为15.4%~53.5%。
A novel and practical synthetic method for the preparation of 2alkyl2,2diallylacetic acids was reported. 2Alkyl4pentenioc acids was obtained by esterification of 2alkylacetic acids with allyl chloride and Claisen rearrangement catalyzed by sodium hydride. After esterification and Claisen rearrangement of 2alkyl4pentenioc acids, 2alkyl2,2diallylacetic acids was obtained in 15.4%~53.5% yield.
出处
《华东理工大学学报(自然科学版)》
CAS
CSCD
北大核心
2003年第2期210-213,共4页
Journal of East China University of Science and Technology
基金
国家自然科学基金资助项目(29902001)