血红素蛋白质微小仿生模型的设计

Minimalist of Heme-protein Design

金属蛋白种类繁多 ,功能各异 ,血红素蛋白质是其中非常重要的一类。为了研究其结构 功能之间的关系 ,人们采用不同的方法设计了多种血红素蛋白质的微小仿生模型。本文介绍了螺旋束血红素蛋白质 ,螺旋 血红素

Metalloproteins utilize a relatively small number of metal-based prosthetic groups to serve numerous and diverse chemical functions. The Heme-protein family represents a fascinating example in this respect. A large number of heme-protein minimalisted models have been developed using quite different strategies for understanding the structure-function relationship in heme-proteins. Here, design and characterization of α-helix bundles heme-roteins and peptide-sandwiched proteins are reviewed.