糖尿病病人尿中核黄素含量测定及临床分析

Measurement of urine riboflavin in patients with diabetes mellitus

目的 :了解 2型糖尿病病人体内核黄素代谢水平及其临床意义。 方法 :利用荧光光度法测定 2型糖尿病病人尿中核黄素的含量 ,按正常人群标准分为正常组和偏低组 ,然后调查确诊患有白内障、周围神经炎、高血压、冠心病和贫血等并发症的情况。 结果 :85例 2型糖尿病病人尿中的核黄素平均含量低于我国正常人群水平 ,其中偏低组合并有白内障、高血压或冠心病率高于正常组 (P <0 .0 5 ) ;周围神经炎和贫血在两组间无显著差异 (P >0 .0 5 )。 结论 :增加 2型糖尿病病人食物中核黄素的摄入量或口服补充核黄素 ,可能有益于预防糖尿病某些并发症的发生。

Objectives:To investigate the metabolism of riboflavin in type 2 of diabetes mellitus(DM) patient. Methods:The content of riboflavin in the urine in type 2 of DM patient was detected and the complication related to DM was examined. Results:The average content of urine riboflavin in DM patients was lower than that of normal people, and the prevalence rate of cataract, hypertension and coronary heart disease was higher in the low content group of urine riboflavin than that in the normal group( P <0.05). Conclusions:To increase the intake of riboflavin may be beneficial to decrease the incidence rate of complication in DM patients.