鼻塞对阻塞性睡眠呼吸暂停综合征发病影响的研究

Influence of nasal obstruction on obstructive sleep apnea syndrone

目的:探讨鼻塞对阻塞性睡眠呼吸暂停综合征(OSAS)发病的影响。方法:对18例诊断为鼻塞和腭咽平面阻塞的OSAS患者,单纯行鼻腔手术改善通气,6个月后复诊。结果:12例睡眠阻塞症状缓解,其中4例效果明显;6例无效。睡眠呼吸紊乱指数(AHI)由术前的29.9±2.1降至22.8±2.7;夜间最低血氧饱和度由(75.0±2.9)％升至(83.4±2.3)％;而体重指数无明显差异。无效组与有效组的术前AHI值差异有显著性意义。结论:鼻塞是OSAS的重要致病因素,早期治疗解除鼻塞是预防OSAS发病的重要措施之一;长期鼻塞引发的OS-AS患者,早期通过鼻腔手术解除鼻塞是治疗OSAS的有效方法之一。

Objective: To explore the influence of nasal obstruction on obstructive sleep apnea syndrome (OSAS). Method; 18 patients with OSAS concomitant,with nasal obstruction and palatopharyngeal obstruction were only operated on nasal cavity to improve ventilation, followed-up six months. Result; 12 cases were reported remission, 4cases efficient, and Gcases unchanged, apnea and hypopnea index (AHI) decreased from 29. 9 + 2. 1 to 22. 8 + 2. 7. and lowest SaO, (LoSaO2)increased from (75 + 2. 9)% to (83. 4 + 2. 3)%. There was no significant difference for body mass index (BMI), but there was significant difference for preoperativc AHI between non-effective groups and effective groups. Conclusion; Nasal obstruction is an important pathogenic factor. It is a necessary method to prevent OSAS by relieving nasal obstruction earlier and operation on nasal cavity is an effective method for the management of OSAS concomitant with nasal obstruction.