沙漠热环境负重行军对淋巴细胞HSP70的影响

Effects of marching with load of 1.5 kilograms in dry-heat desert on heat shock protein 70 in human lymphocyte

目的 探讨沙漠热环境负重行军者血淋巴细胞HSP70的变化规律。方法 对沙漠干热环境中以不同速度和时间负重行军的 5 4名战士和 14名对照者血淋巴细胞HSP70进行对比分析。结果 相同行军时间的不同行军速度间淋巴细胞HSP70有显著性差异 (P <0 0 5 ) ;3 5km/h行军 3h组淋巴细胞HSP70明显高于对照和行军 2h组 (P <0 0 5 ) :5 0km/h行军 1 2h组血淋巴细胞HSP70明显高于对照和行军 3h组 (P <0 0 5 )。结论 随行军速度和时间的增加 ,淋巴细胞HSP70增高 ;当行军速度和时间达到一定水平后 ,机体淋巴细胞HSP70明显增加。血淋巴细胞HSP70作为热损伤和热耐受的监测指标较血浆HSP70敏感。

Objective To explore the regulation of heat shock protein 70(HSP70) in human lymphocyte in case of marching without load in dry-heat desert.Methods The lymphocyte HSP70 of 54 marchers at different speed at different time and 14 controls were detected.Results There was signficant difference between different speeds at the same time( P <0 05);The lymphocyte HSP70 of group for 3 hours was obviously more than that of the control and the group for 2 hours at 3.5km/h;The level of HSP70 for 1 and 2 hours is more than the control at 5.0km/h( P <0 05),but less than for 3 hours( P <0 05).Conclusion The lymphocyte HSP70 increased with speed and time.The blood lymphocyte HSP70 was more sensitive than plasma HSP70 in the monitor of heat injure and heat tolerance.