摘要
慢性鼻窦炎(chronic rhinosinusitis,CRS)属于耳鼻咽喉头颈外科的常见疾病,是鼻腔及鼻窦黏膜的慢性炎症疾病。CRS发病率高,全球发病率为5%~15%,其在亚洲发病率超过10%。CRS的病因繁多、发病机制错综复杂而且临床疗效不理想[1-2]。临床上,约10%的患者经规范化治疗后病情无法得到有效控制,发展为难治性CRS。
Chronic nasal-sinusitis is a chronic inflammatory disease characterized by persistent inflammation in the nasal and nasal mucosa.The pathogenesis of CRS is extremely complex and there is currently a lack of effective therapy.The reason for inaccurate diagnosis and invalid treatment of CRS is its sophisticated and unclear mechanism.The pathogenesis of CRS from Asian populations is neutrophil infiltration mediated by Th1/Th17 mixture.Consequently,exploring the function of neutrophil in the pathogenesis of CRS plays an important role in clinical diagnosis and treatment for CRS patients in China.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2019年第8期789-792,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
