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无关供者造血干细胞移植治疗合并侵袭性真菌感染的急性白血病2例并文献复习 被引量:1

Unrelated donor hematopoietic stem cell transplantation for acute leukemia with invasive fungal infection:Two cases report and literature review
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摘要 感染是异基因造血干细胞移植(allogeneic hematopoietic stem cell transplantation,alloHSCT)成功的主要障碍,深部侵袭性真菌感染(invasive fungal infection,IFI)容易导致allo-HSCT失败。既往认为合并深部IFI是allo-HSCT的禁忌证,但新型强力低毒抗真菌药物的出现及广泛抗.
出处 《临床血液学杂志》 CAS 2019年第1期52-54,共3页 Journal of Clinical Hematology
关键词 造血干细胞移植 无关供者 侵袭性真菌感染 急性白血病 hematopoietic stem cell transplantation unrelated donor invasive fungal infection acute leukemia
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  • 1Ninin E,Milpied N,Moreau P,et al. Longitudinal study ofbacterial, viral, and fungal infections in adult recipients of bonemarrow transplants. Clin Infect Dis, 2001,33 :41-47.
  • 2Upton A, Kirby KA, Carpenter P, et al. Invasive aspergillosisfollowing hematopoietic cell transplantation: outcomes andprognostic factors associated with mortality. Clin Infect Dis,2007,44:531-540.
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  • 4Sun YQ, Xu LP, Liu DH, et al. The incidence and risk factors ofinvasive fungal infection after haploidentical haematopoietic stemcell transplantation without in vitro T-cell depletion. Clin MicrobiolInfect, 2012,18:997-1003.
  • 5Herbrecht R,Caillot D,Cordonnier C,et al. Indications andoutcomes of antifungal therapy in French patients withhaematological conditions or recipients of haematopoietic stem celltransplantation. J Antimicrob Chemother, 2012,67 :2731-2738.
  • 6Ruhnke M,Bohme A, Buchheidt D,et al. Diagnosis of invasivefungal infections in hematology and oncology—guidelines from theInfectious Diseases Working Party in Haematology and Oncology ofthe German Society for Haematology and Oncology ( AGIHO). AnnOncol, 2012,23:823-833.
  • 7Lass-Florl C,Mutschlechner W, Aigner M,et al. Utility of PCRin diagnosis of invasive fungal infections : real-life data from amulticenter study. J Clin Microbiol, 2013 ,51 :863-868.
  • 8血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(第三次修订)[J].中华内科杂志,2010,49(5):451-454. 被引量:196

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