《ANP32A regulates histone H3 acetylation and promotes leukemogenesis》解读

Comments on "ANP32A regulates histone H3 acetylation and promotes leukemogenesis"

本文最初发表于2018年《Leukemia》杂志上,文章题录为:Yang X,Lu B,Sun X,et al.ANP32Aregulates histone H3acetylation and promotes leukemogenesis[J].Leukemia,2018,32:1587-1597。在本研究中,我们发现ANP32A能够促进AML发生;ANP32A通过调控组蛋白H3乙酰化修饰影响脂质代谢等下游关键通路;靶向ANP32A及其下游通路有望成为白血病治疗的新策略。