原发乳腺弥漫大B细胞淋巴瘤的诊治进展

Progress of diagnosis and treatment in primary breast diffuse large B-cell lymphoma

原发乳腺淋巴瘤(primary breast lymphoma,PBL)是局限于一侧或两侧乳腺组织的淋巴瘤,可伴或者不伴腋窝淋巴结的肿大[1-4]。PBL是结外淋巴瘤中罕见的类型,于1959年首次报道,约占结外淋巴瘤的1%~3%,在乳腺的恶性肿瘤中约占0.5%[1-4]。近年来该病的发病率逐年增加,但目前尚无相关的诊断和治疗标准。本文将从该病的临床表现、诊断标准、辅助检查、治疗方式等方面进行阐述。1 临床表现该病的临床表现多样.

Primary breast lymphoma is a rare type of lymphoma with distinct characters.Diffuse large B-cell lymphoma is the most common pathological type.In recent years,the incidence of the disease has increased a lot,but there is no guideline for clinical reference,which undoubtedly increases the difficulties in the diagnosis and treatment of the disease.This article will introduce the clinical manifestations,accessory examination,diagnosis criteria,and further exploring the treatment after recurrence and the administration of new targeted drugs.