某院铜绿假单胞菌临床分布及耐药性分析

Clinical distribution and drug resistance of Pseudomonas aeruginosa

目的分析我院铜绿假单胞菌(PAE)的临床分布和耐药性特点。方法回顾性分析我院2012年1月-2014年12月临床分离的961株PAE非重复株标本分布及耐药性。结果 961株PAE的标本来源主要为呼吸道分泌物及创面,分别占79.8%和10.3%;科室分布主要为呼吸内科(22.4%)、ICU病区(25.5%)及神经外科(12.5%);2012-2014年PAE对庆大霉素、哌拉西林及头孢哌酮等的耐药率略有上升趋势。结论 PAE易导致医院感染发生,应加强我院耐药性监测,以指导临床医师合理使用抗菌药物。

AIM To analyse the distribution and drug resistance of Pseudomonas aeruginosa(PAE)of our hospital.METHODS Distribution and drug resistance of PAE,which were collected from Jan.2012 to Dec.2014,were retrospectively analyzed.RESULTS A total of 961 strains of PAE were isolated in the three years,which were mainly from the respiratory tract secretions(79.8%),followed by the secretions of wound surface(10.3%).They were mainly distributed in department of respiratory medicine(22.4%),intensive care unit(25.5%) and department of neurosurgery(12.5%).The drug resistance rate of PAE to amikacin,piperacillin and cefoperazone etc.,showed an upward trend.CONCLUSION PAE is liable to cause hospital infections.It is necessary to strengthen the monitoring of antimicrobial drug resistance so as to guide the reasonable clinical use of antimicrobial drugs.