烧伤病区病原菌结构的变化

The Change in Species of Pathogens in Burn Unit

目的 对 7年来我院烧伤病区病原菌结构的变化进行分析。方法 对本院烧伤病区病原菌分离、鉴定的相关资料进行统计分析。结果 革兰阳性菌特别是金黄色葡萄球菌在病原菌中的构成比逐渐升高 ,1996年至今始终占病原菌构成比的第 1位。而铜绿假单胞菌和大肠埃希菌等革兰阴性菌的的构成比逐年下降 ;同时原来不是主要病原菌的阴沟肠杆菌、不动杆菌和肺炎克雷伯菌等构成比有明显升高。结论 临床抗生素使用方面的变化以及其他相关抗感染措施的采用是导致病原菌结构变化的重要因素 ,而了解病原菌的结构及其变化趋势对于加强抗感染治疗的针对性和主动性 ,取得最佳的感染防治效果具有重要意义。

OBJECTIVE To analyze the change in species of pathogens in burn unit. METHODS The isolation and identification data of bacteria isolated from burn unit in a 7 year period were investigated. RESULTS The species ratio of Staphylococcus aureus was gradually increased in pathogens and ranked the first in pathogens of burn unit from 1996 to 2001, at the same time, the ratio of Pseudomonas aeruginosa, Escherichia coli and Serratia were decreased,whereas the proportions of Enterobacter cloacae,Klebsiella pneumoniae,and Acinetobacter were aggrandized in pathogens. CONCLUSIONS The antibiotic administration may be the one of the key factors to result in the change in species of pathogens. It is important to consider the species of pathogens and their variety trend in burn unit for infection prophylaxis and treatment.